Table 3 Adverse events (All cycles)
N = 12 | CTC-AE grade (Ver. 4.03) | ||||
|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 3/4 (%) | |
Leukopenia | 1 | 3 | 3 | 0 | 3 (25 %) |
Neutropenia | 2 | 3 | 3 | 0 | 3 (25 %) |
Anemia | 4 | 1 | 1 | 0 | 1 (8 %) |
Thrombocytopenia | 4 | 0 | 1 | 0 | 1 (8 %) |
Febrile Neutropenia | 0 | 0 | 1 | 0 | 1 (8 %) |
Hypoalbuminemia | 7 | 1 | 0 | 0 | 0 (0 %) |
T-Bil elevation | 1 | 1 | 0 | 0 | 0 (0 %) |
AST elevation | 6 | 0 | 0 | 0 | 0 (0 %) |
ALT elevation | 4 | 0 | 0 | 0 | 0 (0 %) |
ALP elevation | 4 | 0 | 0 | 0 | 0 (0 %) |
Cre elevation | 3 | 0 | 0 | 0 | 0 (0 %) |
Hyperkalemia | 2 | 0 | 0 | 0 | 0 (0 %) |
Hypercalcemia | 2 | 0 | 0 | 0 | 0 (0 %) |
Hyponatremia | 2 | 0 | 0 | 0 | 0 (0 %) |
Fatigue | 3 | 1 | 1 | 0 | 1 (8 %) |
Anorexia | 4 | 3 | 1 | 0 | 1 (8 %) |
Weight loss | 1 | 1 | 0 | 0 | 0 (0 %) |
Nausea | 1 | 2 | 1 | 0 | 1 (8 %) |
Vomiting | 2 | 0 | 0 | 0 | 0 (0 %) |
Constipation | 2 | 4 | 0 | 0 | 0 (0 %) |
Perforation (colon) | 0 | 0 | 1 | 0 | 1 (8 %) |
Hypertension | 1 | 2 | 0 | 0 | 0 (0 %) |
Epistaxis | 3 | 0 | 0 | 0 | 0 (0 %) |
Stroke | 0 | 1 | 0 | 0 | 0 (0 %) |
Urticaria | 1 | 1 | 0 | 0 | 0 (0 %) |
Pruritus | 2 | 0 | 0 | 0 | 0 (0 %) |
Pneumonitis | 2 | 0 | 0 | 0 | 0 (0 %) |