After low and high dose-rate interstitial brachytherapy followed by IMRT radiotherapy for intermediate and high risk prostate cancer

Table 3 The multiple logistic regression analysis for increment of IPSS. The multiple logistic regression analysis of whether t-IPSS incresased by ten or over ten points during 91–180 days after ISBT. Similary, i-IPSS increment of five or over five points during the same time period was analyzed

IPSS	Factor	Odds ratio (95 % of confidence level)	p value
t-IPSS + 10	D50 % of urethra	1.021 (1.001-1.041)	0.035*
	D50 % of urethra	1.039 (1.009-1.069)	0.011^*
	D50 % of base of urethra	-	0.868
i-IPSS + 5	V90 of urethra	-	0.657
i-IPSS + 5	V90 of base of urethra	-	0.411
	V100 of urethra	-	0.427
	Brachytherapy technique	-	0.100

t-IPSS + 10 (D₅₀ % of urethra): Model x test: p<0.001, Determine predictive value: 80.6 %; i-IPSS + 5 (D₅₀ % of urethra): Model x test: p<0.001, Determine predictive value: 90.3 %
Abbreviations: IPSS international Prostate Symptom Score, t-IPSS total score of IPSS, i-IPSS total score of IPSS about irritative symptom, Dx% minimum dose delivered to x% of the organ volume, Vx proportion of volume receving x Gy. The Gy indicates the dose which was converted into the EQD2
The * indicates a variable that has a significant difference

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