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Table 6 association of CCL2 rs3760396 polymorphism with pathological subtypes of lung cancer

From: Genetic polymorphism rs3760396 of the chemokine (C-C motif) ligand 2 gene (CCL2) associated with the susceptibility of lung cancer in a pathological subtype-specific manner in Han-ancestry Chinese: a case control study

Genetic model

Comparison

RRR

p-value

95 % CI_Lower

95 % CI_Upper

Squamous cell carcinoma

Reference Outcome

  

Adenosquamous carcinoma

   

 allelic

G vs C

6.77

< 0.001*

2.58

17.74

 Dominant

GC/GG vs CC

12.91

< 0.001*

4.10

40.61

 genotypic

GC vs CC

14.42

< 0.001*

4.48

46.41

 

GG vs CC

    

Adenocarcinoma

    

 allelic

G vs C

1.73

0.09

0.93

3.24

 Dominant

GC/GG vs CC

1.76

0.10

0.89

3.47

 genotypic

GC vs CC

1.68

0.15

0.83

3.40

  1. Note: Inclusion of clinical stages as a covariate in case only analysis on the association of CCL2 rs3760396 polymorphism with pathological subtypes of lung cancer. Squamous cell carcinoma was used as a reference subtype. CCL2 chemokine (C-C motif) ligand 2 gene, RRR relative risk ratio, CI confidence interval
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BMC Cancer

ISSN: 1471-2407

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