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Table 6 association of CCL2 rs3760396 polymorphism with pathological subtypes of lung cancer

From: Genetic polymorphism rs3760396 of the chemokine (C-C motif) ligand 2 gene (CCL2) associated with the susceptibility of lung cancer in a pathological subtype-specific manner in Han-ancestry Chinese: a case control study

Genetic model Comparison RRR p-value 95 % CI_Lower 95 % CI_Upper
Squamous cell carcinoma Reference Outcome   
Adenosquamous carcinoma    
 allelic G vs C 6.77 < 0.001* 2.58 17.74
 Dominant GC/GG vs CC 12.91 < 0.001* 4.10 40.61
 genotypic GC vs CC 14.42 < 0.001* 4.48 46.41
  GG vs CC     
Adenocarcinoma     
 allelic G vs C 1.73 0.09 0.93 3.24
 Dominant GC/GG vs CC 1.76 0.10 0.89 3.47
 genotypic GC vs CC 1.68 0.15 0.83 3.40
  1. Note: Inclusion of clinical stages as a covariate in case only analysis on the association of CCL2 rs3760396 polymorphism with pathological subtypes of lung cancer. Squamous cell carcinoma was used as a reference subtype. CCL2 chemokine (C-C motif) ligand 2 gene, RRR relative risk ratio, CI confidence interval