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Table 4 Cox proportional hazards model univariate and multivariate analyses of individual parameters for correlations with overall survival (342 cases)

From: MEK5 overexpression is associated with the occurrence and development of colorectal cancer

  Univariate analysis Multivariate analysis
  All cases Mean survival (months) P value HR (95 % CI) P value
Sex    0.988   
 Female 157 94.2    
 Male 185 91.7    
Age at diagnosis (years)    0.144   
  < 60 159 94.9    
  ≥ 60 183 90.6    
Tumor location    0.023 1.76(1.17–2.67) 0.008
 Rectum 160 96.5    
 Colon 182 88.8    
TNM stage    0.000 2.75(1.82–4.16) 0.000
 I-II 195 106.1    
 III-IV 147 73.0    
Differentiation grade    0.001 2.40(1.34–4.28) 0.003
 Well and Moderate 312 96.5    
 Poorly 30 60.9    
Serosal invasion    0.411   
 Yes 73 95.8    
 No 269 93.1    
MEK5 expression    0.012 1.51(1.01–2.25) 0.045
 Normal expression 233 95.2    
 Over expression 109 84.8