From: MEK5 overexpression is associated with the occurrence and development of colorectal cancer
Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|
All cases | Mean survival (months) | P value | HR (95 % CI) | P value | |
Sex | 0.988 | ||||
Female | 157 | 94.2 | |||
Male | 185 | 91.7 | |||
Age at diagnosis (years) | 0.144 | ||||
< 60 | 159 | 94.9 | |||
≥ 60 | 183 | 90.6 | |||
Tumor location | 0.023 | 1.76(1.17–2.67) | 0.008 | ||
Rectum | 160 | 96.5 | |||
Colon | 182 | 88.8 | |||
TNM stage | 0.000 | 2.75(1.82–4.16) | 0.000 | ||
I-II | 195 | 106.1 | |||
III-IV | 147 | 73.0 | |||
Differentiation grade | 0.001 | 2.40(1.34–4.28) | 0.003 | ||
Well and Moderate | 312 | 96.5 | |||
Poorly | 30 | 60.9 | |||
Serosal invasion | 0.411 | ||||
Yes | 73 | 95.8 | |||
No | 269 | 93.1 | |||
MEK5 expression | 0.012 | 1.51(1.01–2.25) | 0.045 | ||
Normal expression | 233 | 95.2 | |||
Over expression | 109 | 84.8 |