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Table 3 Cox proportional hazards model univariate and multivariate analyses of individual parameters for correlations with disease-free survival (342 cases)

From: MEK5 overexpression is associated with the occurrence and development of colorectal cancer

  Univariate analysis Multivariate analysis
  All cases Mean survival (months) P value HR (95 % CI) P value
Sex    0.938   
 Female 157 93.5    
 Male 185 92.9    
Age at diagnosis (years)    0.754   
  < 60 159 91.0    
  ≥ 60 183 94.7    
Tumor location    0.011 1.850 (1.23–2.78) 0.003
 Rectum 160 95.2    
 Colon 182 84.2    
TNM stage    0.000 2.70 (1.81–4.01) 0.000
 I-II 195 120.7    
 III-IV 147 64.6    
Differentiation grade    0.000 1.88(1.07–3.32) 0.029
 Well and Moderate 312 96.6    
 Poorly 30 61.8    
Serosal invasion    0.230   
 Yes 73 98.8    
 No 269 92.3    
MEK5 expression    0.000 1.64 (1.09–2.47) 0.017
 Normal expression 233 98.2    
 Over expression 109 79.3