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Table 2 Correlation between MEK5 expression and clinicopathologic characteristics

From: MEK5 overexpression is associated with the occurrence and development of colorectal cancer

   MEK5 expression  
  All cases Low (%) High (%) P value
Sex     0.648
 Female 157 105(66.9) 52(33.1)  
 Male 185 128(69.2) 57(30.8)  
Age at diagnosis (years)     0.697
  < 60 159 110(69.2) 49(30.8)  
  ≥ 60 183 123(67.2) 60(32.8)  
Tumor location     0.815
 Rectum 160 108(67.5) 52(32.5)  
 Colon 182 125(68.7) 57(31.3)  
pT (invasion depth)     0.001
 T1 5 5(100) 0(0)  
 T2 57 50(87.7) 7(12.3)  
 T3 242 157(64.9) 85(35.1)  
 T4 38 21(55.3) 17(44.7)  
pN (lymph node metastasis)     0.001
 N0 205 155(75.6) 50(24.4)  
 N1 87 47(54) 40(46)  
 N2 50 31(62) 19(38)  
pM (distant metastasis)     0.026
 M0 312 218(69.9) 94(30.1)  
 M1 30 15(50) 15(50)  
TNM stage     0.000
 I 48 45(93.8) 3(6.3)  
 II 147 104(70.7) 43(29.3)  
 III 117 69(59) 48(41)  
 IV 30 15(50) 15(50)  
Differentiation grade     0.002
 Well 28 25(89.3) 3(10.7)  
 Moderate 284 194(68.3) 90(31.7)  
 Poorly 30 14(46.7) 16(53.3)  
Pathology type     0.812
 Villous adenocarcinoma 21 16(76.2) 5(23.8)  
 Tubular adenocarcinoma 277 187(67.5) 90(32.5)  
 Mucinous adenocarcinoma 29 19(65.5) 10(34.5)  
 Others 15 11(73.3) 4(26.7)  
Serosal invasion     0.227
 Yes 73 54(74) 19(26)  
 No 269 179(66.5) 90(33.5)  
  1. Low, negative or weak; high, moderate or intense