Fig. 1
From: MEK5 overexpression is associated with the occurrence and development of colorectal cancer
Immunohistochemical staining of MEK5 protein in normal colorectal mucosa, colorectal adenoma, and CRC. (Left panels, ×100, right panels, ×400). (a) Weak MEK5 expression in normal colorectal mucosa; (b) moderate MEK5 expression in adjacent normal colorectal mucosa; (c) weak MEK5 expression in colorectal adenoma; (d) moderate MEK5 expression in colorectal adenoma; (e) weak MEK5 expression in well differentiated CRC; (f) strong MEK5 expression in poorly differentiated CRC (mucinous adenocarcinoma). The fig. (g and h) show the MEK5 expression in the occurrence of CRC: Elevated MEK5 expression in the atypical hyperplasia and tumor cells of CRC tissue compared with those of adjacent normal mucosa