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Fig. 1 | BMC Cancer

Fig. 1

From: Rationale and design of the German-Speaking Myeloma Multicenter Group (GMMG) trial ReLApsE: a randomized, open, multicenter phase III trial of lenalidomide/dexamethasone versus lenalidomide/dexamethasone plus subsequent autologous stem cell transplantation and lenalidomide maintenance in patients with relapsed multiple myeloma

Fig. 1

ReLApsE trial overview. Rd: 28 day cycle of lenalidomide (25 mg p.o. daily on days 1-21) and low-dose dexamethoasone (40 mg p.o. daily on days 1, 8, 15, 22); cyclophosphamide: 2 g*m−2 i.v. daily on days 1 and 2; G-CSF: Filgrastim 10 μg*kg−1*d−1 or lenograstim 300 μg*m−2*d−1 s.c. daily from day 5 until the end of apheresis; HDCT: High dose chemotherapy (melphalan 100 mg*m−2 i.v. daily on days -3 and -2); ASCT: Autologous stem cell transplantation (≥ 2*106 CD34+ cells*kg bw−1 on day 0); R-maintenance: Lenalidomide maintenance (10 mg p.o. daily)

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