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Table 1 AIF dependence is related to metabolic phenotype [53] and sensitivity to glycolytic inhibition in pancreatic cancer cells

From: Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells

  Relative metabolic phenotype [53] Sensitivity to glycolytic disruption Sensitivity to AIF ablation
Glycolysis/PPP Fatty acid/ OXPHOS
PANC-1 Moderate Moderate Insensitive Sensitive
BxPC-3 Moderate Moderate Insensitive Sensitive
HPAC Low High Insensitive Sensitive
HPAF-II High Moderate Moderately sensitive Moderately sensitive
MIA PaCa-2 High Low Sensitive Insensitive