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Fig. 5 | BMC Cancer

Fig. 5

From: Relevance of internal time and circadian robustness for cancer patients

Fig. 5

Wrist temperature and activity pattern for two patients, one with a low DI between wrist temperature and motor activity rhythms (a) and other with a high DI (b). Mean waveforms for the baseline pre-chemo period (4 days) are represented. Wrist temperature rhythm is drawn as a solid black line and motor activity is shown as grey bars. In addition, the five consecutive hours of maximal and minimal values for temperature and motor activity and their central timing (M5 and L5, respectively) are indicated by grey rectangles. Wrist temperature error (the standard error of the mean, SEM) is represented by dotted lines above and below the wrist temperature series. Motor activity SEM is omitted in this figure for reasons of clarity. a corresponds to a patient with a DI = 0.00; note that M5 = 03:50 h and L5 = 03:50 h coincide. b corresponds to a patient with a DI = 0.63; note not only the difference in timing for M5 = 04:40 h; L5 = 12:10 h, but also the lack of any overlapping

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