Fig. 3

Distribution of phase markers. Individual values (n = 24) for M5 (central timing for the 5 consecutive hours of maximal values), in the case of temperature (T), or L5 (central timing for the 5 consecutive hours of minimal values) for the remaining variables (activity (A), position (P) and TAP) in each period studied (before, during and after chemotherapy) are represented as black circles, black rhombus, white squares and black stars, respectively. The standard nighttime period is drawn as a black bar between midnight and eight a.m.. In addition to individual values, the mean ± SEM for each variable is also drawn in grey