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Table 4 Staining patterns of each immunohistochemical marker in sample groups of non-progressor or with progressors and sporadic colorectal neoplasia

From: Comparative analysis of copy number variations in ulcerative colitis associated and sporadic colorectal neoplasia

Genes UC-NP n = 20 UC-P n = 18 S-CRN n = 14 1 p-value 2 p-value 3 p-value
p53 + 7 (35 %) 16 (89 %) 9 (64 %) 0.0009 0.1 0.1
<50 % 2 (28.6 %) 1 (6.2 %) 1 (11.1 %)
>50 % 5 (71.4 %) 15 (93.8 %) 8 (89 %)
CCND1 + 12 (60 %) 17 (94 %) 14 (100 %) 0.02 0.01 NS
<25 % 9 (75 %) 5 (29.4 %)
>25 % 3 (25 %) 12 (70.6 %) 14 (100 %)
AMACR + 9 (50 %) 6 (43 %)
<5 % 2 (22.2 %)
>5 % 7 (77.8 %) 6 (100 %)
EGFR + 10 (56 %) 7 (50 %)
<5 % 2 (20 %) 1 (14.3 %)
>5 % 8 (80 %) 6 (85.7 %)
C-MYC + 4 (20 %) 10 (56 %) 7 (50 %) 0.04 0.1 NS
<5 % 2 (50 %) 1 (10 %) 2 (28.6 %)
>5 % 2 (50 %) 9 (90 %) 5 (71.4 %)
ERBB2 + 2 (10 %) 4 (22 %) 6 (43 %) NS 0.04 NS
<5 % 2 (100 %) 2 (33.3 %)
>5 % 4 (100 %) 4 (66.7 %)
FNDC3A + 11 (55 %) 16 (88.9 %) 14 (100 %) 0.032 0.004 NS
  1. The number and percentage of patients with a positive immunostaining according to staining intensity and the percentage of stained cells in these patients.1 p-value: statistical comparison between UC-NP vs UC-P; 2 p-value: statistical comparison between UC-NP vs S-CRN; 3 p-value: statistical comparison between UC-P vs S-CRN