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Table 1 The summary of quantitative real-time PCR results for potential six candidate oncogenes amplification in study group of samples

From: Comparative analysis of copy number variations in ulcerative colitis associated and sporadic colorectal neoplasia

Gene

S-CRN n = 102

UC-CRN n = 31

Controls n = 30

1 p-value

2 p-value

MYC

 Amp n (%)

23 (22.5 %)

5 (16.1 %)

0

0.004

0.05

 Nor n (%)

79 (77.5 %)

26 (83.9 %)

30 (100 %)

  

MYCN

 Amp n (%)

16 (15.7 %)

2 (6.5 %)

1(3.3 %)

NS

NS

 Nor n (%)

86 (84.3 %)

29 (93.5 %)

29 (96.7 %)

  

EGFR

 Amp n (%)

21 (20.6 %)

1 (3.2 %)

2 (6.7 %)

NS

NS

 Nor n (%)

81 (79.4 %)

30 (96.8 %)

28 (93.3 %)

  

FNDC3A

 Amp n (%)

21 (20.6 %)

2 (6.5 %)

1 (3.3 %)

0.04

NS

 Nor n (%)

81 (79.4 %)

29 (93.5 %)

29 (96.7 %)

  

CCND1

 Amp n (%)

10 (9.8 %)

3 (9.7 %)

0

NS

NS

 Nor n (%)

92 (91.2 %)

28 (91.3 %)

30 (100 %)

  

CCND2

 Amp n (%)

13(12.7 %)

3 (9.7 %)

1 (3.3 %)

NS

NS

 Nor n (%)

89 (87.3 %)

28 (91.3 %)

29 (96.7 %)

  
  1. Amp: amplification of gene (copy number >2); Nor: normal gene copy (copy number ≤2);n = number of samples;1 p-value: statistical comparison between S-CRN vs Control; 2 p-value: statistical comparison between UC-CRN vs Control; NS: statistically not significant (p > 0.05). S-CRN group is comprised of 98 samples and 4 cell lines