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Table 1 The summary of quantitative real-time PCR results for potential six candidate oncogenes amplification in study group of samples

From: Comparative analysis of copy number variations in ulcerative colitis associated and sporadic colorectal neoplasia

Gene S-CRN n = 102 UC-CRN n = 31 Controls n = 30 1 p-value 2 p-value
MYC
 Amp n (%) 23 (22.5 %) 5 (16.1 %) 0 0.004 0.05
 Nor n (%) 79 (77.5 %) 26 (83.9 %) 30 (100 %)   
MYCN
 Amp n (%) 16 (15.7 %) 2 (6.5 %) 1(3.3 %) NS NS
 Nor n (%) 86 (84.3 %) 29 (93.5 %) 29 (96.7 %)   
EGFR
 Amp n (%) 21 (20.6 %) 1 (3.2 %) 2 (6.7 %) NS NS
 Nor n (%) 81 (79.4 %) 30 (96.8 %) 28 (93.3 %)   
FNDC3A
 Amp n (%) 21 (20.6 %) 2 (6.5 %) 1 (3.3 %) 0.04 NS
 Nor n (%) 81 (79.4 %) 29 (93.5 %) 29 (96.7 %)   
CCND1
 Amp n (%) 10 (9.8 %) 3 (9.7 %) 0 NS NS
 Nor n (%) 92 (91.2 %) 28 (91.3 %) 30 (100 %)   
CCND2
 Amp n (%) 13(12.7 %) 3 (9.7 %) 1 (3.3 %) NS NS
 Nor n (%) 89 (87.3 %) 28 (91.3 %) 29 (96.7 %)   
  1. Amp: amplification of gene (copy number >2); Nor: normal gene copy (copy number ≤2);n = number of samples;1 p-value: statistical comparison between S-CRN vs Control; 2 p-value: statistical comparison between UC-CRN vs Control; NS: statistically not significant (p > 0.05). S-CRN group is comprised of 98 samples and 4 cell lines