TY - JOUR AU - Brodsky, Alexander S. AU - Xiong, Jinjun AU - Yang, Dongfang AU - Schorl, Christoph AU - Fenton, Mary Anne AU - Graves, Theresa A. AU - Sikov, William M. AU - Resnick, Murray B. AU - Wang, Yihong PY - 2016 DA - 2016/04/18 TI - Identification of stromal ColXα1 and tumor-infiltrating lymphocytes as putative predictive markers of neoadjuvant therapy in estrogen receptor-positive/HER2-positive breast cancer JO - BMC Cancer SP - 274 VL - 16 IS - 1 AB - The influence of the tumor microenvironment and tumor-stromal interactions on the heterogeneity of response within breast cancer subtypes have just begun to be explored. This study focuses on patients with estrogen receptor-positive/human epidermal growth factor receptor 2-positive (ER+/HER2+) breast cancer receiving neoadjuvant chemotherapy and HER2-targeted therapy (NAC+H), and was designed to identify novel predictive biomarkers by combining gene expression analysis and immunohistochemistry with pathologic response. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-016-2302-5 DO - 10.1186/s12885-016-2302-5 ID - Brodsky2016 ER -