Table 2 Multivariate analyses of NRM, relapse, treatment-failure and death
From: Prognostic impact of IKZF1 deletion in adults with common B-cell acute lymphoblastic leukemia
Outcome | N | RR (95Â % CI) | P |
|---|---|---|---|
NRM | |||
  IKZF1 deleted vs. not deleted | 66/78 | 0.8 (0.3–2.2) | 0.630 |
 Age: ≥ vs. < 35 y | 55/89 | 3.0 (1.1–8.7) | 0.040 |
Relapse | |||
  IKZF1 deleted vs. not deleted | 66/78 | 2.7 (1.4–5.2) | 0.002 |
 Chemotherapy vs. transplant | 52/92 | 6.0 (3.1–11.6) | 0.000 |
 Male vs. female | 73/71 | 2.0 (1.1–3.9) | 0.030 |
Treatment-failure | |||
  IKZF1 deleted vs. not deleted | 66/78 | 2.1 (1.2–3.6) | 0.007 |
 Chemotherapy vs. transplant | 52/92 | 4.4 (2.6–7.6) | 0.000 |
Death | |||
  IKZF1 deleted vs. not deleted | 66/78 | 2.8 (1.5–5.6) | 0.002 |
 Chemotherapy vs. transplant | 52/92 | 4.1 (2.1–7.8) | 0.000 |
Chemotherapy | |||
  IKZF1 deleted vs. not deleted | 28/24 | 6.5 (2.1–19.7) | 0.001 |
Transplant | |||
  IKZF1 deleted vs. not deleted | 38/54 | 1.5 (0.7–3.6) | 0.336 |