From: In vitro and in vivo activity of melflufen (J1) in lymphoma
Patient no | IC50 melphalan (ÎĽM) | IC50 melflufen (ÎĽM) | Ratio |
---|---|---|---|
1 | 1.7 | 0.018 | 94 |
2 | 6.7 | 0.51 | 13 |
3 | 7.0 | 0.059 | 118 |
4 | 19 | 0.053 | 363 |
5 | 89 | 0.55 | 162 |
6 | 8.5 | 0.12 | 73 |
7 | 29 | 0.11 | 271 |
8 | 6.0 | 0.018 | 337 |
9 | 2.8 | <0.01 | 278 |
10 | 0.73 | 0.0080 | 91 |
11 | 13 | 0.079 | 160 |
12 | 1.2 | 0.0027 | 455 |
13 | 31 | 0.080 | 388 |
14 | NA | NA | NA |
15 | 24 | 0.90 | 27 |
16 | 16 | 0.66 | 24 |
MEAN | 8.4 | 0.078 | 108 |