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Table 1 Correlation between NLK expression and clinicopathological parameters of PCa patients

From: Nemo-like kinase as a negative regulator of nuclear receptor Nurr1 gene transcription in prostate cancer

No NLK protein expression (%) p
High Low
Group     
 BPH 50 31 (62.0) 19 (38.0) .003
 PCa 118 44 (37.3) 74 (62.7)  
Age (year)     
 <70 45 14 (31.1) 31 (68.9) .276
 ≥70 73 30 (41.1) 43 (58.9)  
Gleason score     
 4–6 42 28 (66.7) 14 (33.3) <.001
 7 20 7 (35.0) 13 (65.0)  
 8–10 56 9 (16.1) 47 (83.9)  
CS (TNM)     
T stage     
 T1-T2 56 28 (50.0) 28 (50.0) .007
 T3-T4 62 16 (25.8) 46 (74.2)  
N stage     
 N0 90 39 (43.3) 51 (56.7) .015
 N1 28 5 (17.9) 23 (82.1)  
M stage     
 M0 94 39 (41.5) 55 (58.5) .065
 M1 (bone) 24 5 (20.8) 19 (79.2)  
Nurr1 expression     
 High 84 18 (21.4) 66 (78.6) <.001
 Low 34 26 (76.5) 8 (23.5)  
  1. Statistical analyses were performed by the Pearson χ 2 test, p < 0.05 was considered significant