Fig. 2
From: Antitumor effects of cecropin B-LHRH’ on drug-resistant ovarian and endometrial cancer cells
Cecropin B-LHRH’ induces ultrastructural changes in ES-2 cells. Transmission electron microscope images (a–e), and scanning electron microscope images (f) of a normal ES-2 cell (a); ES-2 cells incubated with 25 μM cecropin B-LHRH’ for 1 h (b–f). Figures b–d illustrate cell membrane blebbing, the disappearance or reduction of microvilli, cell shrinkage, increased cellular granularity, and the formation and separation of apoptotic bodies. e and f show cytoplasm leak. Morphological changes observed in ES-2 cell line