Table 3 Relationships between serum CTSB and CTSD concentrations and clinicopathological characteristics of patients with nasopharyngeal carcinoma
From: Diagnostic values of serum cathepsin B and D in patients with nasopharyngeal carcinoma
Variables | Number | CTSB (mg/L) | P value | CTSD (mg/L) | p value |
|---|---|---|---|---|---|
Median (min–max) | Median (min–max) | ||||
Sex | |||||
Men | 52 | 12.4 (4.4–25.6) | 0.823 | 16.6 (2–42.3) | 0.153 |
Women | 28 | 12.0 (8.0–19.0) | 2.7 (4.6–29.1) | ||
Age, years | |||||
≤ 45 | 42 | 11.9 (4.4–25.6) | 0.855 | 15.3 (3.8–42.3) | 0.086 |
> 45 | 38 | 12.5 (7.8–19.0) | 14.4 (2–28.7) | ||
Smoking | |||||
Yes | 55 | 12.4 (6.5–25.6) | 0.583 | 14.7 (3.8–42.3) | 0.519 |
No | 25 | 12.5 (4.4–19.0) | 15.5 (2–29.6) | ||
Alcohol intake | |||||
Yes | 57 | 12.5 (5.0–25.6) | 0.675 | 14.4 (4.2–42.3) | 0.985 |
No | 23 | 12.4 (4.4–17.5) | 15.3 (2–33.4) | ||
TNM grade | |||||
I + II | 22 | 9.2 (4.4–17.3) | 0.0001 | 8.7 (2.0–24.7) | 0.002 |
III + IV | 58 | 13.1 (8.9–25.6) | 15.7 (2.8–42.60) | ||
EBV/VCA-IgA | |||||
≤ 1:160 | 44 | 11.9 (6.5–25.6) | 0.693 | 14.9 (4.2–33.4) | 0.441 |
≥ 1:320 | 36 | 12.6 (4.4–19.0) | 12.6 (2.0–42.6) | ||