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Table 3 Relationships between serum CTSB and CTSD concentrations and clinicopathological characteristics of patients with nasopharyngeal carcinoma

From: Diagnostic values of serum cathepsin B and D in patients with nasopharyngeal carcinoma

Variables Number CTSB (mg/L) P value CTSD (mg/L) p value
   Median (min–max)   Median (min–max)  
Sex
 Men 52 12.4 (4.4–25.6) 0.823 16.6 (2–42.3) 0.153
 Women 28 12.0 (8.0–19.0)   2.7 (4.6–29.1)  
Age, years
  ≤ 45 42 11.9 (4.4–25.6) 0.855 15.3 (3.8–42.3) 0.086
  > 45 38 12.5 (7.8–19.0)   14.4 (2–28.7)  
Smoking
 Yes 55 12.4 (6.5–25.6) 0.583 14.7 (3.8–42.3) 0.519
 No 25 12.5 (4.4–19.0)   15.5 (2–29.6)  
Alcohol intake
 Yes 57 12.5 (5.0–25.6) 0.675 14.4 (4.2–42.3) 0.985
 No 23 12.4 (4.4–17.5)   15.3 (2–33.4)  
TNM grade
 I + II 22 9.2 (4.4–17.3) 0.0001 8.7 (2.0–24.7) 0.002
 III + IV 58 13.1 (8.9–25.6)   15.7 (2.8–42.60)  
EBV/VCA-IgA
  ≤ 1:160 44 11.9 (6.5–25.6) 0.693 14.9 (4.2–33.4) 0.441
  ≥ 1:320 36 12.6 (4.4–19.0)   12.6 (2.0–42.6)  
  1. Notes: CTSB cathepsin B, CTSD cathepsin D, TNM tumor node metastasis, EBV Epstein-Barr virus, VCA-IgA viral capsid antigen IgA