Table 3 The results of pathway analysis
Pathway name | P value (ACFP vs control)/gene number in pathway | |
|---|---|---|
Lower dose | High dose | |
Apoptosis | 0.000971/12 | 0.000781/13 |
Chemokine signaling pathway | 0.003907/20 | 0.001615/19 |
ErbB signaling pathway | 0.030382/10 | 0.014949/11 |
mTOR signaling pathway | 0.022528/7 | 0.020496/9 |
Insulin signaling pathway | 0.037667/13 | 0.028081/14 |
Prostate cancer | 0.038960/10 | 0.023229/12 |
Glutathione metabolism | 0.039118/5 | 0.016997/6 |
beta-Alanine metabolism | 0.040715/4 | 0.025722/5 |
Acute myeloid leukemia | 0.041365/9 | 0.030514/11 |
VEGF signaling pathway | 0.042746/11 | 0.0451753/9 |
Chronic myeloid leukemia | 0.043575/10 | 0.043688/10 |
Cell cycle | 0.044920/7 | 0.040853/7 |
Valine, leucine and isoleucine degradation | 0.046396/7 | 0.041547/8 |
Glycerolipid metabolism | 0.046614/7 | 0.042819/7 |
Fatty acid metabolism | 0.047829/6 | 0.039429/7 |
Amyotrophic lateral sclerosis (ALS) | 0.048708/7 | 0.045332/5 |
T cell receptor signaling pathway | 0.049384/11 | 0.048102/11 |
B cell receptor signaling pathway | 0.049921/8 | 0.040102/9 |
Regulation of actin cytoskeleton | 0.049938/19 | 0.039208/14 |
Endometrial cancer | 0.069635/8 | 0.049471/9 |
Pathways in cancer | 0.101147/20 | 0.047471/25 |
Adipocytokine signaling pathway | 0.104896/5 | 0.049791/7 |
MAPK signaling pathway | 0.106127/17 | 0.047937/17 |
Epithelial cell signaling in Helicobacter pylori | 0.115779/5 | 0.049997/6 |