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Table 2 The down-regulated expression profiling of genes related to apoptosis in ACFP-treated human primary ovarian cancer cell in vitro

From: The milk-derived fusion peptide, ACFP, suppresses the growth of primary human ovarian cancer cells by regulating apoptotic gene expression and signaling pathways

Genebank ID Gene symbol Gene description Ratio (ACFP/control)
Low dose High dose
NM_000598 BCL-xl bcl2-like 1 0.28 0.19
NM_000207 AKT1 v-akt murine thymoma viral oncogene homolog 1 0.29 0.27
NM_000995 CDC25C cell division cycle 25C 0.29 0.32
NM_000891 CCNB1 cyclinB1 0.30 0.21
NM-022931 RAB18 RAB18, member RAS oncogene family 0.30 0.25
NM-084450 ZNF512 zinc finger protein 512 0.31 0.47
NM-060561 RINT-1 Rad50-interacting protein 1 0.32 0.17
NM-005429 POLH polymerase (DNA directed), eta 0.33 0.12
NM-004638 MYLK myosin, light polypeptide kinase 0.33 0.23
NM_063035 BCORL1 BCL6 co-repressor-like 1 0.35 0.25
NM-009448 MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.36 0.41
NM-051176 TCF/LEF1 lymphoid enhancer-binding factor 1 0.36 0.35
NM_005595 MAPK3/ERK1 mitogen-activated protein kinase 3 0.36 0.35
NM_003678 ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.36 0.43
NM-005322 PLA2G5 phospholipase A2, group V 0.36 0.46
NM-084299 C17orf37 chromosome 17 open reading frame 37 0.39 0.38
NM-005682 PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.39 0.49
NM_023533 PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5, p101 0.39 0.44
NM_002868 GRK4 G protein-coupled receptor kinase 4 0.42 0.37
NM-001544 CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.43 0.48
NM-003488 IGFBP5 insulin-like growth factor binding protein 5 0.45 0.23
NM-054984 PINX1 PIN2-interacting protein 1 0.45 0.47
NM-002970 GTF2IP1 general transcription factor IIi pseudogene 1 0.47 0.24
NM_002869 GRK5 G protein-coupled receptor kinase 5 0.47 0.47
NM_000573 BAG1 BCL2-associated athanogene 0.48 0.33
NM-007378 UPP1 uridine phosphorylase 1 0.48 0.42
NM_002870 GRK6 G protein-coupled receptor kinase 6 0.49 0.26
NM-008995 TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.49 0.41
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BMC Cancer

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