Table 1 Demographic and clinical characteristics of the 296 matched case–control study and the 608 case-only study
Cases | Controls | All cases | ||||||
|---|---|---|---|---|---|---|---|---|
Variables | N = 296 | N = 296 | P-value | N = 608 | ||||
N | (%) | N | (%) | N | (%) | Deatha (N = 48) | ||
Study site1 | ||||||||
South | 296 | (100.0) | 296 | (100.0) | 227 | (37.3) | 19 | |
North | - | - | 381 | (62.7) | 29 | |||
Age (yrs) | ||||||||
Mean ± SD | 71.3 ± 7.4 | 70.9 ± 8.0 | 0.622 | 71.6 ± 8.6 | ||||
<65 | 58 | (19.6) | 64 | (21.6) | 0.430 | 133 | (21.9) | 8 |
≥65 | 229 | (77.4) | 215 | (72.6) | 471 | (77.5) | 40 | |
Missing | 9 | 17 | 4 | |||||
BMI (kg/m2) | ||||||||
Mean ± SD | 24.2 ± 3.1 | 24.1 ± 3.2 | 0.742 | 24.3 ± 3.2 | ||||
<24 | 130 | (43.9) | 134 | (45.3) | 0.967 | 277 | (45.6) | 27 |
24– < 27 | 90 | (30.4) | 89 | (30.1) | 207 | (34.0) | 13 | |
≥27 | 41 | (13.9) | 43 | (14.5) | 98 | (16.1) | 5 | |
Missing | 35 | 30 | 26 | 3 | ||||
Education | ||||||||
<high school | 100 | (33.8) | 111 | (37.5) | 0.861 | 175 | (27.8) | 18 |
High school | 85 | (28.7) | 86 | (29.1) | 225 | (37.0) | 17 | |
>high school | 66 | (22.3) | 66 | (22.3) | 178 | (29.3) | 13 | |
Missing | 45 | 33 | 30 | 0 | ||||
Marital status* | ||||||||
Single/widowed/separated/divorced | 44 | (14.9) | 30 | (10.1) | 0.047* | 55 | (9.0) | 6 |
Married | 205 | (69.3) | 231 | (78.0) | 520 | (85.5) | 42 | |
Missing | 47 | 35 | 33 | |||||
Vasectomy | ||||||||
No | 215 | (72.6) | 199 | (67.2) | 0.628 | 516 | (84.9) | 39 |
Yes | 10 | (3.4) | 7 | (2.4) | 17 | (2.8) | 0 | |
Missing | 71 | 90 | 75 | 9 | ||||
Family history of PC | ||||||||
No | 226 | (76.4) | 245 | (82.8) | 0.243 | 523 | (86.0) | 43 |
Yes | 17 | (5.7) | 11 | (3.7) | 32 | (5.3) | 3 | |
Missing | 53 | 40 | 53 | |||||
Cigarette Smoking | ||||||||
No | 153 | (51.7) | 159 | (53.7) | 0.561 | 293 | (48.2) | 20 |
Yes | 143 | (48.3) | 135 | (45.6) | 315 | (51.8) | 28 | |
Missing | 0 | 2 | 0 | 0 | ||||
Alcohol drinking | ||||||||
No | 199 | (67.2) | 208 | (70.2) | 0.459 | 428 | (70.4) | 28 |
Yes | 95 | (32.1) | 87 | (29.4) | 179 | (29.4) | 20 | |
Missing | 2 | 1 | 1 | 0 | ||||
Betel nut chewing | ||||||||
No | 281 | (94.9) | 281 | (94.9) | 0.845 | 578 | (95.1) | 44 |
Yes | 13 | (4.4) | 12 | (4.1) | 28 | (4.6) | 3 | |
Missing | 2 | 3 | 2 | 1 | ||||
Clinical stageb | ||||||||
Localized | 290 | (47.7) | 7 | |||||
Locally advanced | 158 | (26.0) | 7 | |||||
Bone metastasis | 154 | (25.3) | 34 | |||||
Missing | 6 | 0 | ||||||
Gleason score | ||||||||
<6 | 255 | (41.9) | 11 | |||||
7 | 191 | (31.4) | 12 | |||||
8-10 | 154 | (25.3) | 25 | |||||
Missing | 8 | 0 | ||||||
Preoperative PSA (ng/ml) | ||||||||
<10 | 152 | (25.0) | 5 | |||||
10- < 20 | 143 | (23.5) | 4 | |||||
≥20 | 295 | (48.5) | 38 | |||||
Missing | 18 | 1 | ||||||