Fig. 3

Knocking down CDK4 induced miR-15a expression by suppressing c-Myc expression. a. Stable suppression of CDK4 reduced the expression of c-Myc in NPC cells. b. si-Myc inhibited the expression of c-Myc in NPC cells. c. Transiently inhibited c-Myc by siRNA stimulated the expression of miR-15a. (*P < 0.05)