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Fig. 4 | BMC Cancer

Fig. 4

From: Radical nephrectomy and regional lymph node dissection for locally advanced type 2 papillary renal cell carcinoma in an at-risk individual from a family with hereditary leiomyomatosis and renal cell cancer: a case report

Fig. 4

Immunohistochemistry. Immunohistochemical analysis of Nrf2 expression using anti-Nrf2 monoclonal antibody in HLRCC-associated kidney cancer (a-c) (X 200 magnification. Scale bars showed 200 μm). a, b: Much of cancer cells showed diffuse strong brown staining in a membrane and cytoplasm for anti-Nrf2 antibody in the proband (III-9) (a) and maternal cousin (III-4) (b) with non-prior therapy. c: Some of viable cancer cell showed weak reaction in the present case (III-8) with neoadjuvant axitinib therapy. d: Clear cell renal cell carcinoma tissues randomly selected for this study showed negative staining

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