Fig. 5

Dasatinib does not function via Src kinase in non-metastatic ccRCC cell lines. a Western blots and showing siRNA knockdown of NT or Src kinase in 769-P and 786–O. b-c Graph showing effect of 1, 10, 50 and 100 nM Dasatinib (dark bars) and saracatinib (light bars) on (b) proliferation and (c) apoptosis in the presence of NT (solid bars) and Src siRNA (checked bars) in 769-P and 786-O cells. d, e Photographs and (f) quantification graphs showing effects of inhibitors on migration as assessed by wound healing in 769-P and 786-O cells (n = 3-4; * = 0.05, ** = 0.01, *** = 0.001)