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Table 5 Univariate and multivariate overall survival analysis of patients who underwent rectal cancer resection (Cox proportional hazard model)

From: Role of autophagy-related protein expression in patients with rectal cancer treated with neoadjuvant chemoradiotherapy

 

Variable

Univariate analysis

Multivariate analysis

HR

95 % CI

P value

HR

95 % CI

P value

Age

 

1.010

0.97 – 1.06

0.521

   

Sex

Female vs. Male

0.489

0.16 – 1.48

0.206

0.379

0.12 – 1.16

0.088

cT stage

cT4 vs. cT2-3

4.840

1.11 – 21.1

0.036

3.305

0.72 – 15.15

0.124

cN stage

cN1-2 vs. cN0

3.070

1.11 – 8.54

0.031

4.572

1.33 – 15.71

0.016

Histological grade

Poorly vs. Well/Mod

2.870

0.84 – 9.86

0.094

12.264

2.06 – 73.14

0.006

CEA

 

1.010

1.00 – 1.02

0.135

1.007

1.00 – 1.02

0.203

LDH

 

0.999

0.99 – 1.01

0.719

   

ypCR

Yes vs. Nos

0.338

0.12 – 0.94

0.038

0.176

0.04 – 0.80

0.025

LC3β expression

High vs. Low

1.290

0.52 – 3.17

0.581

1.460

0.60 – 3.58

0.409

Beclin-1 expression

High vs. Low

0.942

0.36 – 2.48

0.904

0.773

0.23 – 2.58

0.675

  1. HR hazard ratio, CI confidence interval, CEA carcinoembryonic antigen, LDH lactate dehydrogenase, cT clinical T stage, cN clinical N stage
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