Fig. 3From: Copy number of the Adenomatous Polyposis Coli gene is not always neutral in sporadic colorectal cancers with loss of heterozygosity for the geneElectropherogram showing D5S346 microsatellite analysis of DNA used to determine loss of heterozygosity of APC. a Normal mucosa indicating the patient’s two alleles, A6 and A10. b Ascending colon carcinoma. The A10 allele is diminished, resulting in significant reversal of the relative intensities of the two bandsBack to article page