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Fig. 2 | BMC Cancer

Fig. 2

From: Copy number of the Adenomatous Polyposis Coli gene is not always neutral in sporadic colorectal cancers with loss of heterozygosity for the gene

Fig. 2

Capillary electrophoresis pattern for APC copy number. The Y-axis is the fluorescence signal intensity and the X-axis is the fragment size in base pairs, extending from 60 to 420 (indicated across the top). The peaks below 110 base pairs are quality control fragments. The 26 peaks highlighted by black circles are APC gene probe fragments, and the remaining 13 unhighlighted peaks are reference probe fragments. a. DNA from normal colon tissue. b DNA from colon carcinoma from the same patient showing diminished intensity with all APC probe fragments, relative to the normal tissue peaks

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BMC Cancer

ISSN: 1471-2407

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