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Table 1 Deregulation of miRNA expression in different types of thyroid tumors according to some literature data

From: miRNA profiling, detection of BRAF V600E mutation and RET-PTC1 translocation in patients from Novosibirsk oblast (Russia) with different types of thyroid tumors

Cancer type miRNA Expression Detection method Reference
Papillary thyroid carcinoma (PTC) 187, 221, 222, 146b, 155, 122a, 31, 205, 224 Up-regulated RT-qPCR [3]
  146b, 181b, 21, 221, 222 Up-regulated RT-qPCR [4]
  221, 222 Up-regulated RT-qPCR [5]
  146, 221, 222 Up-regulated microarray, RT-qPCR [6]
  221, 222, 181b Up-regulated microarray, RT-qPCR [7]
  146b, 221, 222 Up-regulated RT-qPCR [8]
  221, 222, 21, 31, 181b, 223, 224 Up-regulated microarray, RT-qPCR [9]
  218, 300, 292, 345, 30c Down-regulated microarray, RT-qPCR [9]
Follicular variant of papillary carcinoma (FVPTC)/PTC 146b-3p, 146-5p, 221, 222 375, 551b, 181-2-3p, 99b-3p Up-regulated microarray, RT-qPCR [10]
Medullary thyroid cancer (MTC) 323, 370, 129, 137, 10a, 124a, 224, 127, 9, 154 Up-regulated RT-qPCR [3]
  183, 375 Up-regulated RT-qPCR [11]
Follicular thyroid carcinoma (FTC) 187, 224, 221, 339, 183, 222 Up-regulated RT-qPCR [3]
  199b-5p, 144-5p, 144-3p, 199b-3p Down-regulated microarray, RT-qPCR [12]
  192, 197, 328, 346 Up-regulated microarray, RT-qPCR [13]
Thyroid follicular adenoma (FA) 31, 339, 183, 221, 224, 205, 210, 190 Up-regulated RT-qPCR [3]
  199b-5p, 144-5p, 663, 199b-3p Down-regulated microarray, RT-qPCR [12]
  1. miRNAs shown in boldface type were used in our work