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Table 1 Deregulation of miRNA expression in different types of thyroid tumors according to some literature data

From: miRNA profiling, detection of BRAF V600E mutation and RET-PTC1 translocation in patients from Novosibirsk oblast (Russia) with different types of thyroid tumors

Cancer type

miRNA

Expression

Detection method

Reference

Papillary thyroid carcinoma (PTC)

187, 221, 222, 146b, 155, 122a, 31, 205, 224

Up-regulated

RT-qPCR

[3]

 

146b, 181b, 21, 221, 222

Up-regulated

RT-qPCR

[4]

 

221, 222

Up-regulated

RT-qPCR

[5]

 

146, 221, 222

Up-regulated

microarray, RT-qPCR

[6]

 

221, 222, 181b

Up-regulated

microarray, RT-qPCR

[7]

 

146b, 221, 222

Up-regulated

RT-qPCR

[8]

 

221, 222, 21, 31, 181b, 223, 224

Up-regulated

microarray, RT-qPCR

[9]

 

218, 300, 292, 345, 30c

Down-regulated

microarray, RT-qPCR

[9]

Follicular variant of papillary carcinoma (FVPTC)/PTC

146b-3p, 146-5p, 221, 222 375, 551b, 181-2-3p, 99b-3p

Up-regulated

microarray, RT-qPCR

[10]

Medullary thyroid cancer (MTC)

323, 370, 129, 137, 10a, 124a, 224, 127, 9, 154

Up-regulated

RT-qPCR

[3]

 

183, 375

Up-regulated

RT-qPCR

[11]

Follicular thyroid carcinoma (FTC)

187, 224, 221, 339, 183, 222

Up-regulated

RT-qPCR

[3]

 

199b-5p, 144-5p, 144-3p, 199b-3p

Down-regulated

microarray, RT-qPCR

[12]

 

192, 197, 328, 346

Up-regulated

microarray, RT-qPCR

[13]

Thyroid follicular adenoma (FA)

31, 339, 183, 221, 224, 205, 210, 190

Up-regulated

RT-qPCR

[3]

 

199b-5p, 144-5p, 663, 199b-3p

Down-regulated

microarray, RT-qPCR

[12]

  1. miRNAs shown in boldface type were used in our work