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Table 2 Prognostic factors for overall and disease-free survival after colorectal cancer resection

From: Urgent surgery after emergency presentation for colorectal cancer has no impact on overall and disease-free survival: a propensity score analysis

Prognostic factors

Overall survival

Disease free survival

Unadjusteda

Full modelb

Backwards variable selectionc

Unadjusteda

Full modelb

Backwards variable selectionc

HR (95 % CI)

p *

HR (95 % CI)

p*

HR (95 % CI)

p*

HR (95 % CI)

p*

HR (95 % CI)

p *

HR (95 % CI)

p*

Cancer resection

Elective

Reference

0.045

Reference

0.629

Reference

0.043

Reference

0.877

 

Urgent

1.35 (1.02–1.78)

 

1.08 (0.79–1.48)

 

1.33 (1.02–1.74)

 

1.02 (0.76–1.38)

 

Age

years

1.04 (1.03–1.05)

<0.001

1.05 (1.04–1.06)

<0.001

1.05 (1.04–1.06)

<0.001

1.03 (1.03–1.04)

<0.001

1.04 (1.03–1.05)

<0.001

1.04 (1.03–1.05)

<0.001

Sex

m

Reference

0.973

Reference

0.850

Reference

0.478

Reference

0.381

 

w

1.00 (0.84–1.20)

 

0.98 (0.81–1.19)

 

0.94 (0.79–1.12)

 

0.92 (0.76–1.11)

 

Tumor localisation

Cecum

Reference

0.004

Reference

0.002

Reference

0.003

Reference

0.018

Reference

0.026

Reference

0.031

 

Asc. colon

0.72 (0.53–0.96)

 

0.60 (0.44–0.82)

 

0.62 (0.46–0.83)

 

0.76 (0.57–1.02)

 

0.67 (0.49–0.91)

 

0.68 (0.50–0.91)

 
 

Transv. colon

0.81 (0.53–1.23)

 

0.62 (0.40–0.97)

 

0.63 (0.41–0.97)

 

0.78 (0.51–1.18)

 

0.62 (0.40–0.95)

 

0.63 (0.41–0.96)

 
 

Desc. olon

0.87 (0.62–1.22)

 

0.90 (0.63–1.28)

 

0.90 (0.64–1.27)

 

0.94 (0.68–1.31)

 

0.99 (0.70–1.39)

 

1.03 (0.74–1.45)

 
 

Sigm. colon

0.73 (0.56–0.95)

 

0.66 (0.50–0.88)

 

0.68 (0.51–0.89)

 

0.80 (0.62–1.04)

 

0.79 (0.60–1.05)

 

0.83 (0.63–1.08)

 
 

Rectum

0.56 (0.42–0.74)

 

0.57 (0.42–0.79)

 

0.58 (0.43–0.78)

 

0.62 (0.47–0.81)

 

0.70 (0.51–0.95)

 

0.74 (0.56–0.99)

 

Perforation

No

Reference

0.525

Reference

0.492

Reference

0.684

Reference

0.704

 

Yes

1.10 (0.82–1.49)

 

1.13 (0.80–1.58)

 

1.06 (0.79–1.42)

 

1.07 (0.77–1.48)

 

Protec. colostomy

No

Reference

0.929

Reference

0.530

Reference

0.987

Reference

0.783

 

Yes

1.01 (0.77–1.33)

 

1.10 (0.81–1.50)

 

1.00 (0.77–1.31)

 

1.04 (0.77–1.41)

 

Resection status

R0

Reference

<0.001

Reference

0.001

Reference

<0.001

Reference

<0.001

Reference

0.004

Reference

0.003

 

R1/2

3.21 (2.16–4.75)

 

2.22 (1.45–3.38)

 

2.30 (1.52–3.49)

 

3.07 (2.08–4.55)

 

1.97 (1.29–3.02)

 

1.97 (1.30–3.00)

 

UICC Stage

I

Reference

<0.001

Reference

<0.001

Reference

<0.001

Reference

<0.001

Reference

<0.001

Reference

<0.001

 

II

1.28 (0.97–1.69)

 

1.21 (0.89–1.64)

 

1.25 (0.93–1.67)

 

1.41 (1.08–1.85)

 

1.39 (1.03–1.87)

 

1.37 (1.03–1.82)

 
 

III

1.67 (1.27–2.19)

 

1.67 (1.22–2.29)

 

1.74 (1.29–2.36)

 

1.80 (1.38–2.34)

 

1.79 (1.31–2.43)

 

1.75 (1.30–2.36)

 
 

IV

4.02 (3.02–5.35)

 

4.89 (3.45–6.94)

 

5.10 (3.64–7.14)

 

4.83 (3.65–6.40)

 

5.64 (3.99–7.97)

 

5.58 (4.00–7.79)

 

Tumor diameter

mm

1.00 (1.00–1.01)

0.071

1.00 (1.00–1.01)

0.730

1.00 (1.00–1.01)

0.043

1.00 (1.00–1.01)

0.829

Lymph node yield

<12

Reference

0.662

Reference

0.006

Reference

0.007

Reference

0.662

Reference

0.173

 

12+

0.95 (0.77–1.18)

 

0.72 (0.57–0.91)

 

0.73 (0.58–0.91)

 

1.05 (0.85–1.29)

 

0.85 (0.68–1.07)

 

Tumor grading

G1

Reference

0.012

Reference

0.367

Reference

0.001

Reference

0.009

Reference

0.007

 

G2

1.09 (0.65–1.82)

 

1.23 (0.72–2.09)

 

1.07 (0.65–1.77)

 

1.21 (0.72–2.03)

 

1.20 (0.72–2.00)

 
 

G3

1.58 (0.92–2.71)

 

1.41 (0.80–2.47)

 

1.66 (0.98–2.81)

 

1.45 (0.84–2.50)

 

1.42 (0.83–2.45)

 
 

GX

1.33 (0.69–2.57)

 

1.59 (0.81–3.14)

 

1.57 (0.84–2.95)

 

2.44 (1.27–4.68)

 

2.49 (1.31–4.73)

 

Adjuvant chemo.

No

Reference

0.679

Reference

0.042

Reference

0.027

Reference

0.501

Reference

0.142

Reference

0.142

 

Yes

0.96 (0.79–1.17)

 

0.77 (0.60–0.99)

 

0.76 (0.60–0.97)

 

1.07 (0.88–1.29)

 

0.84 (0.66–1.06)

 

0.84 (0.66–1.06)

 
  1. HR Hazard ratios with 95 % confidence intervals (Wald type) and p-values of the likelihood ratio test
  2. Prognostic factors for overall survival in:
  3. *p values for likelihood ratio tes
  4. aone Cox proportional hazards regression analyses for each factor
  5. bCox proportional hazards regression analyses for all factors
  6. cCox proportional hazards regression analyses for all factors after backwards variable selection