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Table 4 Poisson Regression model of relative likelihood of partners giving birth >1 year after cancer diagnosis of the men, expressed as Birth Rate Ratios (BRRs)

From: Birth rates among male cancer survivors and mortality rates among their offspring: a population-based study from Sweden

 

Number of births

Person years

Unadj BRR (95 % CI)

BRRa (95 % CI)

Parity status at diagnosis

 Nulliparous

5706

180421

1.00

1.00

 Parous

2204

307707

0.41 (0.39–0.43)

0.74 (0.69–0.79)

Cancer site

 Melanoma skin

1032

55946

1.00

1.00

 Head & neck

280

23671

1.27 (1.11–1.45)

1.32 (1.15–1.50)

 Digestive

544

51622

0.73 (0.66–0.81)

0.99 (0.89–1.10)

 Thoracic

91

9954

2.28 (1.84–2.83)

1.83 (1.48–2.27)

 Breast

3

647

3.22 (1.04–10.00)

2.89 (0.93–8.98)

 Prostate

4

30934

0.04 (0.02–0.12)

0.25 (0.09–0.67)

 Reproductive organs

1555

60648

0.96 (0.89–1.04)

0.69 (0.64–0.75)

 Brain & eye

1188

54827

0.89 (0.82–0.97)

0.71 (0.65–0.77)

 Thyroid

674

35597

1.03 (0.94–1.14)

0.90 (0.81–0.99)

 Bone

993

49411

1.05 (0.96–1.15)

0.87 (0.80–0.96)

 Hematopoietic

935

47662

0.89 (0.82–0.97)

0.69 (0.63–0.76)

 Others

611

67210

0.60 (0.55–0.67)

0.92 (0.83–1.01)

Age at diagnosis

 Adulthood (19 to 70 years)

891

24647

1.00

1.00

 Adolescence (13 to 18 years)

6409

441720

1.24 (1.16–1.33)

0.76 (0.69–0.83)

 Childhood (0 to 12 years)

610

21762

0.90 (0.83–0.98)

0.44 (0.38–0.50)

Time since diagnosis

 1 to 5 years

3738

226941

1.00

1.00

 6 to 10 years

2090

111500

1.31 (1.24–1.38)

1.10 (1.04–1.17)

 11 to 20 years

1558

105367

1.23 (1.16–1.30)

1.23 (1.12–1.34)

 21 to 35 years

524

44322

1.63 (1.49–1.79)

2.10 (1.77–2.50)

Attained age

 16 to 25 years

682

31079

1.00

1.00

 26 to 30 years

2160

26385

3.52 (3.23–3.84)

2.74 (2.48–3.01)

 31 to 35 years

2448

35261

3.15 (2.89–3.43)

2.38 (2.15–2.64)

 36 to 40 years

1572

43824

1.88 (1.71–2.05)

1.44 (1.28–1.61)

 41 to 45 years

678

53092

0.90 (0.81–1.00)

0.69 (0.61–0.80)

 46 to 70 years

370

298488

0.31 (0.27–0.35)

0.25 (0.21–0.29)

  1. aAll estimates are adjusted for parity status at diagnosis, cancer site, age and period of diagnosis, time since diagnosis, calendar period, attained age and socio-economic status. Bold number units indicate a significant difference in BRRs