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Table 5 Potential predictors influencing DFS for patients excluding bilateral neck lymph node metastasis

From: Patterns of recurrence after selective postoperative radiation therapy for patients with head and neck squamous cell carcinoma

 

2-y DFS (%)

DFS

yes

no

p value in uni.

p value in multi.

HR

95 % CI

OC

36.9

64.4

0.034*

   

Necrosis in LN

64.9

48.4

0.423

   

Bi-lateral ND

53.0

55.9

0.998

   

NAC

87.5

48.6

0.076

   

Rec

30.6

64.2

0.029*

   

T4

46.7

56.6

0.398

   

LN+ ≥2LN+ ≥2

45.3

76.5

0.032*

0.062

  

Extracapsular extention

52.2

57.1

0.442

   

Positive/close margin

56.1

54.2

0.824

   

Bilateral RT

44.4

67.3

0.146

   

IMRT

60.8

33.3

0.050*

0.162

  

Systemic therapy

43.3

56.5

0.619

   

OC or rec

31.9

74.0

0.004*

0.006

1.696

1.29–1.87

  1. DFS disease free survival, uni. univariate analysis, multi. multivariate analysis, HR hazard ration, CI confidence interval, OC oral cavity, LN lymph node, ND neck dissection, Rec recurrence. *​A P value of ≤0.05 was considered statistically significant