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Table 3 Analysis of iron-related proteins expression in the LN of patients with IDC

From: Local iron homeostasis in the breast ductal carcinoma microenvironment

  

Non-metastized LN

Metastized LN

 
 

Cell type

Mean ± SEM

Mean ± SEM

p

Hepcidin

B cell areas

0.08 ± 0.08

0.62 ± 0.14

0.005

T cell areas

0.15 ± 0.10

0.62 ± 0.14

0.018

M0

2.00 ± 0.00

1.92 ± 0.08

ns

FPN1

B cell areas

1.38 ± 0.14

2.23 ± 0.17

0.002

T cell areas

1.38 ± 0.14

2.23 ± 0.17

0.002

M0

1.92 ± 0.08

2.23 ± 1.17

ns

TFR1

B cell areas

1.92 ± 1.18

1.08 ± 0.27

0.026

T cell areas

1.00 ± 0.11

1.08 ± 0.08

ns

M0

2.00 ± 0.11

2.31 ± 0.13

ns

FT

B cell areas

1.77 ± 0.12

2.77 ± 0.12

<0.001

T cell areas

1.54 ± 0.14

2.62 ± 0.14

<0.001

M0

3.00 ± 0.00

3.00 ± 0.00

ns

  1. Abbreviations: LN Lymph Node, IDC Invasive Ductal Carcinoma, SEM Standard Error of the Mean, M0 Macrophages, FPN1 Ferroportin 1, TFR1 Transferrin Receptor 1, FT Ferritin, NS Not Statistically Significant
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BMC Cancer

ISSN: 1471-2407

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