Fig. 8
From: Local iron homeostasis in the breast ductal carcinoma microenvironment
Representative images of Hepcidin, FPN1, TFR1 and FT immunostaining in non-metastized and metastized lymph nodes. Archived lymph nodes from cases with previously analyzed primary invasive ductal carcinomas were sectioned and subjected to immunohistochemistry, as described in materials and methods. Boxes indicate lymph node areas near metastasis. Note prominent germinal centers in non-metastized lymph nodes (×400 original magnification figures are shown below its × 200 correspondent figures). M, metastasis; LN, lymph node