Skip to main content
Fig. 3 | BMC Cancer

Fig. 3

From: Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model

Fig. 3

cPLA2α inhibition effects in vivo tumor perfusion measured by DCE-MRI. a Longitudinal AUC1min maps from representative control and treated tumors, overlaid on their corresponding high-resolution anatomical images. Only enhancing voxels (voxels in which RSI1min > 1.5) are displayed. Scale bar = 2 mm. b Group medians of tumor-wise median AUC1min values of control (black dots) and treated (grey triangles) tumors. Error bars indicate interquartile ranges. c Dot plot of the changes in tumor-wise median AUC1min values from day 0 to 4 and from day 4 to 7. Horizontal lines indicate group medians. d-e Analogous plots for FEV. * p < 0.05, two-tailed Mann–Whitney U test

Back to article page