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Table 3 Genes selected for the classification task of TAHN-TumorADC Vs. TAHN-TumorSCC

From: On Predicting lung cancer subtypes using ‘omic’ data from tumor and tumor-adjacent histologically-normal tissue

Gene Symbol Gene Name Known Literature Evidence to Cancer
ST18 suppression of tumorigenicity 18, zinc finger Yes [45]
CSTA cystatin A (stefin A) Yes [45, 46]
LPP LIM domain containing preferred translocation partner in lipoma Yes [45]
CROT carnitine O-octanoyltransferase Yes [45]
BDKRB1 bradykinin receptor B1 Yes [47]
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) Yes [48]
TP73 tumor protein p73 Yes [4951]
EFCAB3 EF-hand calcium binding domain 3 Yes
RREB1 ras responsive element binding protein 1 Yes [45]
HIST1H4G histone cluster 1, H4g No
STAR steroidogenic acute regulatory protein Yes
ACSBG2 acyl-CoA synthetase bubblegum family member 2 Yes [45]
DQX1 DEAQ box RNA-dependent ATPase 1 Yes [45]
AQP10 aquaporin 10 Yes [45]
PLEKHA6 pleckstrin homology domain containing, family A member 6 Yes [52, 53]
GCSAM germinal center-associated, signaling and motility No
WFDC5 WAP four-disulfide core domain 5 Yes
KRT7 keratin 7, type II Yes [54]
DCST2 DC-STAMP domain containing 2 Yes [45]
CALML3 calmodulin-like 3 Yes
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 Yes
LRRC17 leucine rich repeat containing 17 Yes [45]
TRIM29 tripartite motif containing 29 Yes [55]
CXCR2 chemokine (C-X-C motif) receptor 2 Yes [45, 56, 57]
HOXD9 homeobox D9 Yes [58]
COL17A1 collagen, type XVII, alpha 1 Yes [45]
LMO3 LIM domain only 3 (rhombotin-like 2) Yes
  1. The list of genes is ordered by their ranks, as selected by ReliefF for the classification task of TAHN-TumorADC Vs. TAHN-TumorSCC. The Entrez gene symbol, and the gene name are listed in the first two columns respectively. The ‘Known Literature Evidence to Cancer’ indicates if links to cancer were detected by the IPA® software. Citations are provided to literature indicating links to adenocarcinoma, squamous-cell carcinoma and carcinoma in lung