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Table 3 Genes selected for the classification task of TAHN-TumorADC Vs. TAHN-TumorSCC

From: On Predicting lung cancer subtypes using ‘omic’ data from tumor and tumor-adjacent histologically-normal tissue

Gene Symbol

Gene Name

Known Literature Evidence to Cancer

ST18

suppression of tumorigenicity 18, zinc finger

Yes [45]

CSTA

cystatin A (stefin A)

Yes [45, 46]

LPP

LIM domain containing preferred translocation partner in lipoma

Yes [45]

CROT

carnitine O-octanoyltransferase

Yes [45]

BDKRB1

bradykinin receptor B1

Yes [47]

AKR1B10

aldo-keto reductase family 1, member B10 (aldose reductase)

Yes [48]

TP73

tumor protein p73

Yes [4951]

EFCAB3

EF-hand calcium binding domain 3

Yes

RREB1

ras responsive element binding protein 1

Yes [45]

HIST1H4G

histone cluster 1, H4g

No

STAR

steroidogenic acute regulatory protein

Yes

ACSBG2

acyl-CoA synthetase bubblegum family member 2

Yes [45]

DQX1

DEAQ box RNA-dependent ATPase 1

Yes [45]

AQP10

aquaporin 10

Yes [45]

PLEKHA6

pleckstrin homology domain containing, family A member 6

Yes [52, 53]

GCSAM

germinal center-associated, signaling and motility

No

WFDC5

WAP four-disulfide core domain 5

Yes

KRT7

keratin 7, type II

Yes [54]

DCST2

DC-STAMP domain containing 2

Yes [45]

CALML3

calmodulin-like 3

Yes

ACAP3

ArfGAP with coiled-coil, ankyrin repeat and PH domains 3

Yes

LRRC17

leucine rich repeat containing 17

Yes [45]

TRIM29

tripartite motif containing 29

Yes [55]

CXCR2

chemokine (C-X-C motif) receptor 2

Yes [45, 56, 57]

HOXD9

homeobox D9

Yes [58]

COL17A1

collagen, type XVII, alpha 1

Yes [45]

LMO3

LIM domain only 3 (rhombotin-like 2)

Yes

  1. The list of genes is ordered by their ranks, as selected by ReliefF for the classification task of TAHN-TumorADC Vs. TAHN-TumorSCC. The Entrez gene symbol, and the gene name are listed in the first two columns respectively. The ‘Known Literature Evidence to Cancer’ indicates if links to cancer were detected by the IPA® software. Citations are provided to literature indicating links to adenocarcinoma, squamous-cell carcinoma and carcinoma in lung