Fig. 1

HPV-16 DNA in oral rinse associates with tumor p16INK4a status. a Detection of HPV-16 DNA in representative oral rinse samples of patients with p16INK4a-positive and p16INK4a-negative tumors using end-point PCR. (b) Analysis of HPV-16 DNA copy number in oral rinse of patients with p16INK4a-positive tumors using quantitative RT-PCR (ND = not detected). No HPV-16 DNA was detected in oral rinse of patients with p16INK4a-negative tumors