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Table 4 Frequencies of APOBEC3 deletion according to clinic-pathological features

From: Analysis of functional germline variants in APOBEC3 and driver genes on breast cancer risk in Moroccan study population

  APOBEC3 deletion
Variable II ID
Estrogen/Progesterone receptor No. (%) No. (%)
ER+/PR+ 103 (45.57) 8 (3.53)
ER+/PR 21 (9.29) 4 (1.76)
ER/PR+ 18(7.96) 1 (0.44)
ER/PR 50(22.12) 3 (1.32)
Tumor size   
<2 cm 26 (11.50) 4 (1.76)
>2 cm 97 (42.92) 8 (3.53)
>5 cm 39 (17.25) 2 (0.88)
Tumor of any size with extension 32 (14.15) 5 (2.21)
Histological grade   
1 7 (3.09) 1 (0.44)
2 127 (56.19) 14 (6.19)
3 56 (24.77) 3 (1.32)
Lymph node status   
Negative 64 (28.31) 8 (3.53)
Positive   
  122 (53.98)  
  10 (4.42)  
Distant metastases   
Negative 158 (69.91) 12 (5.30)
Positive   
  31 (13.71) 7 (3.09)
  1. II homozygous insertion, ID herozygous deletion, No total number, ER estrogen receptors, PR progesterone receptors