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Table 4 Frequencies of APOBEC3 deletion according to clinic-pathological features

From: Analysis of functional germline variants in APOBEC3 and driver genes on breast cancer risk in Moroccan study population

 

APOBEC3 deletion

Variable

II

ID

Estrogen/Progesterone receptor

No. (%)

No. (%)

ER+/PR+

103 (45.57)

8 (3.53)

ER+/PR

21 (9.29)

4 (1.76)

ER/PR+

18(7.96)

1 (0.44)

ER/PR

50(22.12)

3 (1.32)

Tumor size

  

<2 cm

26 (11.50)

4 (1.76)

>2 cm

97 (42.92)

8 (3.53)

>5 cm

39 (17.25)

2 (0.88)

Tumor of any size with extension

32 (14.15)

5 (2.21)

Histological grade

  

1

7 (3.09)

1 (0.44)

2

127 (56.19)

14 (6.19)

3

56 (24.77)

3 (1.32)

Lymph node status

  

Negative

64 (28.31)

8 (3.53)

Positive

  
 

122 (53.98)

 
 

10 (4.42)

 

Distant metastases

  

Negative

158 (69.91)

12 (5.30)

Positive

  
 

31 (13.71)

7 (3.09)

  1. II homozygous insertion, ID herozygous deletion, No total number, ER estrogen receptors, PR progesterone receptors