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Fig. 1 | BMC Cancer

Fig. 1

From: Clinical application of genomic profiling to find druggable targets for adolescent and young adult (AYA) cancer patients with metastasis

Fig. 1

Mutation frequency and mutation spectrum of AYA cancers. a Somatic mutation frequencies of pediatric, AYA and adult cancers are shown. Mutation frequencies of AYA cancers were assessed using somatic mutations annotated as nonsynonymous SNVs, synonymous SNVs, nonsense mutations, stop-loss mutations, splicing mutations, frameshift indels, in-frame indels, and noncoding RNA. Mutation frequencies for other cancers were derived from published data from the same regions [19]. b The mutation spectrum of AYA cancers (transition and transversion frequency) was assessed using SNVs processed with MuTect in whole-exome regions

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