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Fig. 5 | BMC Cancer

Fig. 5

From: Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer

Fig. 5

NCe-FA inhibits proliferation and angiogenesis of ovarian tumors in vivo. a Representative Ki-67 staining of the tumor tissue, indicating proliferating cells, from various treatment groups (200×). The counts of positive Ki-67 cells from 5 high powered fields (×400) in 3 different xenografts from each group is presented as a bar graph. ***p < 0.001, #p < 0.05. b Representative CD31 staining of the tumor tissue representing vessel formation from the various treatment groups (200×). Number of positive staining vessels were counted per field from 5 high powered fields (×400) in 3 different xenografts from each group and is presented as a bar graph. c Representative vimentin staining of the tumor tissue from the various treatment groups (400×). Cells with positive membrane stain were counted per field from 5 high powered fields (×400). ***p < 0.001; ns, non-significant

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