Fig. 5
From: Binimetinib inhibits MEK and is effective against neuroblastoma tumor cells with low NF1 expression
Neuroblastoma cell lines sensitive to binimetinib show lower levels of NF1 protein expression. a A panel of neuroblastoma cell lines was analyzed by Western blot for NF1 protein expression levels. Actin was used as a loading control. b Densitometry analysis was performed to quantify relative NF1 protein levels in neuroblastoma tumor cell lines sensitive or resistant to binimetinib