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Table 2 Interrelationship of p-Nrf2 and Ki67 expression in normal pancreatic ducts and PanINs, initial scores were dichotomized by the median score and refitted into 2 groups of low and high expression

From: The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of pro-tumorigenic functions of TGF-β1

 

Normal ducts (n = 22)

PanINs (n = 20)

p-value

Marker

Low

High

Low

High

p-Nrf2

16/21

5/21

3/20

17/20

0.002

Ki67

12/22

10/22

0/19

19/19

0.001

  1. In two cases, no PanINs were detectable
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BMC Cancer

ISSN: 1471-2407

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