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Table 4 Comparison of cell cycle distribution after TKTL1 knockdown and overexpression

From: Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells

Treatment (LM-MEL-59)

Sub G1 (%)

G0-G1 (%)

S (%)

G2-M (%)

 Control siRNA

8.27

48.26

38.84

12.89

  TKTL1 siRNA

7.9

58.17

30.71

11.11

  p Value

0.78

0.004

0.01

0.65

Treatment (LM-MEL-44)

Sub G1 (%)

G0-G1 (%)

S (%)

G2-M (%)

 Empty vector control

18.05

79.55

17.39

3.05

  TKTL1 pcDNA

8.89

65.55

31.42

3.05

  p Value

0.02

0.001

0.01

0.99

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BMC Cancer

ISSN: 1471-2407

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