Fig. 5

TKTL1 enhances invasive behaviour in melanoma. Melanoma cells were plated out and transfected with either 10nM control siRNA or TKTL1 specific siRNA and subjected to invasion assay. a Representative images of invasion of LM-MEL-59 is shown (scale bar = 100 μm). b The graph shows the total number of invasive cells counted. c Invasiveness of melanoma cells LM-MEL-44 after treatment with empty vector control or TKTL1 pcDNA was tested, images captured (scale bar = 100 μm) and d invasion was quantified as above. Values are mean ± SD of three independent experiments in triplicate (*p < 0.05, **p < 0.005)