Fig. 6

The effect of METCAM/MUC18 expression on levels of various key parameters expressed in the tumor lysates, which may affect the tumor growth. Tumor lysates were used in the western blot analysis by using various antibodies, as described in “Methods”. a The summary of Western blot results of levels of various key parameters are shown, and their quantitative results are shown in (b) Bax/BCl2 ratios, c PCNA, d LDH-A, e VEGF, f pan-AKT, g Phospho-AKT(Ser473), and h Phospho-AKT(Ser473)/pan-AKT ratios. P values were determined by using the Student’s t test (1-tailed distribution-type 2/3 method) to analyze the data between the tumor lysates from the METCAM clone 2D clone and those from the Control (Vector) Clone 3D