Fig. 2
From: METCAM/MUC18 is a novel tumor and metastasis suppressor for the human ovarian cancer SKOV3 cells
Effects of huMETCAM/MUC18 expression on the in vitro motility (a) and invasiveness (b) of SK-OV-3 clones/cells. a For the motility test, the METCAM clone 2D and the Control (Vector) clone 3D of SK-OV-3 cells were used. Six hours after seeding to the top wells, cells migrating to the bottom wells were determined as described in “Methods”. Means and standard deviations of triplicate values of the motility tests are indicated. P value, which was determined by analyzing two sets of data with the Student’s t test by using the one-tailed distribution-type 2 method, was 0.014, indicating that the result was statistically different. b For invasiveness test, the METCAM clone 2D and the Control (Vector) clone 3D of SK-OV-3 cells were used. Six hours after seeding cells to the top wells, cells migrating to the bottom wells were determined as described in “Methods”. Means and standard deviations of triplicate values of the invasiveness tests are indicated. P value, which was determined by analyzing two sets of data with the Student’s t test by using the one-tailed distribution-type 2 method, was 0.0015, indicating that the result was statistically different