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Table 3 Treatment of patients

From: Treatment and outcome of 32 patients with distant metastases of Hürthle cell thyroid carcinoma: a single-institution experience

Patient number Initial surgery Residual tumor after surgery RAI ablation of thyroid remnant RAI uptake RAI applications: ablation and therapy (Number) RAI cumulative dose (mCi) Neoadjuvant ChT ChT Preoperative EBRT (Dose in Gy) EBRT - neck and mediastinum (Dose in Gy) EBRT of metastases Surgery for metastases or recurrence
1 TT R0 No - 0 - No No No No No No
2 LO R1 Yes No 1 129 No No No Yes (50) No No
3 LO R1 Yes Yes 7 1066 No No No Yes (50) No No
4 LO R2 Yes No 1 94 Yes Yes Yes (36) Yes (36 + 15) Ribs, thorax No
5 TT R1 Yes Yes 4 500 Yes Yes No Yes (56) Lumbal vertebra, left hip and left pelvis No
6 LO R1 Yes Yes 8 1201 Yes Yes No No Thoracic vertebra - rwice No
7 PT R0 Yes No 2 250 No Yes No No Frontal part of skull, left orbita Resection of right clavicle
8 TT + RND R1 Yes No 1 100 Yes Yes No No Lungs twice No
9 TT R0 Yes No 1 94 No No No No No No
10 TT + RND R1 Yes Yes 8 1355 Yes Yes No Yes (50) No No
11 LO + RND R1 Yes Yes 8 1156 Yes Yes No Yes (45) Left hip twice, thorax, right hip, brain, right clavicle No
12 TT R1 Yes Yes 9 1278 Yes Yes No No Thoracic vertebra, pelvis, cervical vertebra Laminectomy
13 TT R1 No - 0 - No No No No No No
14 TT R0 Yes Yes 5 779 No No No No No No
15 TT R0 Yes No 1 92 No No No No No Left hip replacemnt
16 LO R0 Yes Yes 6 1090 No No No No No Right nephrectomy
17 TT R0 Yes No 1 106 No No No No No No
18 TT R0 Yes No 1 261 No No No No No No
19 LO R0 Yes Yes 2 350 No No No No No No
20 TT R2 Yes No 1 100 No No No Yes (50) No Tracheal shaving of recurrence
21 PT R2 Yes Yes 2 230 No No No No No No
22 TT R0 Yes Yes 2 300 No No No No Base of skull, lungs, right neck No
23 TT + RND R1 Yes No 1 100 Yes Yes No Yes (49) Clavicle No
24 PT R1 Yes Yes 9 1296 No No No Yes (50) No No
25 TT R0 Yes No 2 244 No No No No No No
26 TT R0 Yes Yes 3 382 No No No No No No
27 TT + RND R1 Yes No 1 95 No Yes No Yes (50) Sternum, clavicle, right tibia No
28 LO R1 Yes Yes 11 1523 No Yes No Yes (50) No No
29 LO R2 Yes No 2 263 Yes Yes No Yes (51) Mediastinum, lungs Tracheostomy, mRND
30 LO R0 Yes Yes 2 230 No No No No Mediastinum, lungs Resection of lung metastasis and twice brain matastasis
31 TT R0 Yes Yes 3 393 No No No No No Parotidectomy, mRND
32 TT R0 Yes No 1 95 No Yes No No Pelvis, left elbow, lumbar vertebra 6 x lung metastasis, 5 x bone metastasis, mediastinal lymph nodes, liver metastasis, axillary lymphadenectomy
  1. Legend: TT total or near total thyroidectomy, LO lobectomy, PT partial thyroidectomy, RND modified radical neck dissection, RAI radioiodine, ChT chemotherapy, EBRT external beam radiotherapy
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