Fig. 4

Human LNCaP cells are able to have ADAM19 over-expressed and ADAM19 over-expression reduces LNCaP cell proliferation. a LNCaP cells were transfected with either empty vector (pCR3.1) or human ADAM19 vector (pCR3.1 hADAM19) for 48 h before conducting ADAM19 immunocytochemistry. 100x magnification. Insert shows cytoplasmic staining of over-expressed ADAM19. b LNCaP cell proliferation was measured by MTS assay 3, 5, and 7 days after cells were transfected with empty vector or ADAM19 expressing vector. Mean + SEM. c Photomicrographs of LNCaP cells transfected with empty vector (pCR3.1) or ADAM19 expressing vector (pCR3.1 hADAM19) after 7 days post-transfection. 100x magnification; n = 12 samples/cell type/time point; *p < 0.05