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Table 3 Immunoreactivity of KGHR1-scFv antibody in human tumour tissues and cell lines

From: A novel anti-p21Ras scFv antibody reacting specifically with human tumour cell lines and primary tumour tissues

Immunoreactivity (HSCOREsa)

Immunocytochemistry

Tumour tissues

Cases

Primary tumour tissues

Normal tissues

Tumour cell lines

Results

Colorectal cancer

30

180.54 ± 79.21

7.31 ± 2.13

BGC853

+

Gastric cancer

25

150.17 ± 64.31

7.13 ± 1.99

MKN28

+

Oesophageal cancer

25

151.42 ± 59.13

8.21 ± 2.38

HCT116

+

Bladder cancer

25

149.37 ± 79.27

7.23 ± 2.15

QGY7703

+

Lung adenocarcinoma

20

199.45 ± 69.11

8.13 ± 2.17

SMMC-7721

+

Lung squamous cell carcinoma

20

185.37 ± 71.64

7.53 ± 2.23

HepG2

+

Lung small cell carcinoma

19

146.25 ± 83.00

7.78 ± 2.17

MDA-MB-231

+

Papillary thyroid carcinoma

20

191.67 ± 82.71

7.93 ± 2.76

MDA-MB-435

+

Hepatocarcinoma

22

168.25 ± 79.33

8.47 ± 3.18

MCF7

+

Prostate carcinoma

25

145.37 ± 75.35

8.52 ± 3.43

HeLa

+

Breast cancer

24

165.73 ± 63.28

7.93 ± 2.56

SKOV3

+

Endometrial cancer

30

153.32 ± 57.00

8.73 ± 3.63

Hep2

+

Glioma

20

131.50 ± 42.59

10.28 ± 5.00

T24

+

Renal cell carcinoma

24

89.61 ± 53.73

11.27 ± 4.91

  
  1. aMean ± SD