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Fig. 4 | BMC Cancer

Fig. 4

From: The anti-fibrotic agent pirfenidone synergizes with cisplatin in killing tumor cells and cancer-associated fibroblasts

Fig. 4

In vivo nude mouse model of lung CAFs and A549 (1:1) treated intraperitoneally with 200 mg/kg pirfenidone (Pirf; day 0–27) and 5 mg/kg cisplatin (Cis; day 0, 3, 6, 21, 24, 27) or the combination of both drugs. a Graph of the tumor measurements throughout the entire study. b Scatter plot on last day (day 43) of tumor measurements. Each group consisted of 5 mice. The experiment was done twice with similar trends. *P < 0.05

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